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Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
专利权人:
Ltd.;Platform Brightworks Two
发明人:
Andersson, Borje S.,Valdez, Benigno C.,Tarrand, Jeffrey
申请号:
AU2012250050
公开号:
AU2012250050B2
申请日:
2012.04.20
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous composition that comprises a lipophilic pharmaceutical agent, and an amphiphilic polymeric solvent such as PEG400 but essentially free of organic solvents and non-solubilized particles. The composition may be further diluted with a desired aqueous diluent such as an infusion fluid for parenteral administration to a subject such as a human. The compositions may be useful for the treatment for diseases or conditions that are sensitive to lipophilic agents, such as infectious diseases, malignant or autoimmune diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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