DEBIEN, LAURENT PIERRE PAUL,JAEN, JUAN CARLOS,KALISIAK, JAROSLAW,LAWSON, KENNETH V.,LELETI, MANMOHAN REDDY,LINDSEY, ERICK ALLEN,MILES, DILLON HARDING,NEWCOMB, ERIC,POWERS, JAY PATRICK,ROSEN, BRANDON R
申请号:
CA3009196
公开号:
CA3009196A1
申请日:
2017.01.06
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Compounds that modulate the conversion of AMP to adenosine by 5'- nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5'-nucleotidase, ecto is also provided.