MODULATORS OF 5'-NUCLEOTIDASE, ECTO AND THE USE THEREOF

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专利权人:

ARCUS BIOSCIENCES; INC.

发明人:

DEBIEN, Laurent,JAEN, Juan,KALISIAK, Jaroslaw,LAWSON, Kenneth V.,LELETI, Manmohan Reddy,LINDSEY, Erick,MILES, Dillon Harding,NEWCOMB, Eric,POWERS, Jay Patrick,ROSEN, Brandon Reid,SHARIF, Ehesan UI

申请号：

SG11201805506Y

公开号：

SG11201805506YA

申请日:

2017.01.06

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

Compounds that modulate the conversion of AMP to adenosine by 5′-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5′-nucleotidase, ecto is also provided.

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