DEBIEN, Laurent, Pierre Paul,JAEN, Juan, Carlos,KALISIAK, Jaroslaw,LAWSON, Kenneth V.,LELETI, Manmohan Reddy,LINDSEY, Erick, Allen,MILES, Dillon Harding,NEWCOMB, Eric,POWERS, Jay Patrick,ROSEN, Brando
申请号:
EP17736459
公开号:
EP3399984A4
申请日:
2017.01.06
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Compounds that modulate the conversion of AMP to adenosine by 5′-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5′-nucleotidase, ecto is also provided.