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Immunomodulatory compositions comprising a polymer matrix and an oil phase
专利权人:
Ivan Coulter;Monica Torres Rosa;Edward Charles Lavelle;Bernard Francis McDonald;Vincenzo Aversa
发明人:
Ivan Coulter,Bernard Francis McDonald,Vincenzo Aversa,Monica Torres Rosa,Edward Charles Lavelle
申请号:
US13390085
公开号:
US09878036B2
申请日:
2010.08.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A pharmaceutical composition comprising a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising at least one immunomodulator selected from an adjuvant, an antigen or a combination thereof. A method of manufacturing shaped compositions comprises mixing an aqueous solution of a water-soluble polymer with an oil-based liquid to form a water-in-oil emulsion, at least one of the aqueous solution and the oil-based liquid comprising an antigen or an adjuvant or a combination thereof, and then causing or allowing the resultant suspension to solidify into one or more beads or other shaped elements.
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