Ivan Coulter,Bernard Francis McDonald,Vincenzo Aversa,Mónica Torres Rosa,Edward Charles Lavelle
申请号:
US15813636
公开号:
US20180071387A1
申请日:
2017.11.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A pharmaceutical composition comprising a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising at least one immunomodulator selected from an adjuvant, an antigen or a combination thereof. A method of manufacturing shaped compositions comprises mixing an aqueous solution of a water-soluble polymer with an oil-based liquid to form a water-in-oil emulsion, at least one of the aqueous solution and the oil-based liquid comprising an antigen or an adjuvant or a combination thereof, and then causing or allowing the resultant suspension to solidify into one or more beads or other shaped elements.