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immunomodulatory compositions comprising a polymer matrix and an oil phase
专利权人:
Sigmoid Pharma Limited
发明人:
Bernard Francis Mcdonald,Edward Charles Lavelle,Ivan Coulter,Mónica Torres Rosa,Vicenzo Aversa
申请号:
BR112012002963
公开号:
BR112012002963A2
申请日:
2010.08.12
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
A pharmaceutical composition comprising a water-soluble polymer matrix in which are dispersed droplets of oil, the composition comprising at least one immunomodulator selected from an adjuvant, an antigen or a combination thereof. A method of manufacturing shaped compositions comprises mixing an aqueous solution of a water-soluble polymer with an oil-based liquid to form a water-in-oil emulsion, at least one of the aqueous solution and the oil-based liquid comprising an antigen or an adjuvant or a combination thereof, and then causing or allowing the resultant suspension to solidify into one or more beads or other shaped elements.
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