MOSLIN, Ryan M.,WEINSTEIN, David S.,WROBLESKI, Stephen T.,TOKARSKI, John S.,KUMAR, Amit,BATT, Douglas G,LIN, Shuqun,LIU, Chunjian,SPERGEL, Steven H.,ZHANG, Yanlei,BATT, Do
申请号:
LT13811640
公开号:
LT2922846T
申请日:
2013.11.07
申请国别(地区):
LT
年份:
2018
代理人:
摘要:
Compounds having the following formula I:or a stereoisomer or pharmaceutically-acceptable salt thereof, where R, R, R, R, and Rare as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.