MOSLIN, RYAN M.,WEINSTEIN, DAVID S.,WROBLESKI, STEPHEN T.,ZHANG, YANLEI,TOKARSKI, JOHN S.,MERTZMAN, MICHAEL E.,LIU, CHUNJIAN
申请号：
RSP20191041
公开号：
RS59125B1
申请日:
2014.01.16
申请国别(地区):
RS
年份:
2019
代理人:
摘要：
Compounds having the following formula I:or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R<；sup>；1<；/sup>；, R<；sup>；2<；/sup>；, R<；sup>；3<；/sup>；, R<；sup>；4<；/sup>；, and R<；sup>；5<；/sup>；are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα by acting on Tyk-2 to cause signal transduction inhibition.
