Ryan M. MOSLIN,David S. WEINSTEIN,Stephen T. WROBLESKI,John S. TOKARSKI,Amit KUMAR,Douglas G BATT,Shuqun LIN,Chunjian LIU,Steven H. SPERGEL,Yanlei ZHANG
申请号:
HK16103247.7
公开号:
HK1215255A
申请日:
2016.03.21
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
Compounds having the following formula I:or a stereoisomer or pharmaceutically-acceptable salt thereof, where R, R, R, R, and Rare as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.