METHODS TO IDENTIFY IMMUNOGENS BY TARGETING IMPROBABLE MUTATIONS

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专利权人:

DUKE UNIVERSITY

发明人:

Barton F. HAYNES,Kevin J. WIEHE,Mattia BONSIGNORI

申请号：

US16337264

公开号：

US20200031908A1

申请日:

2017.10.03

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention is directed to methods to identify improbable mutations in the heavy or light chain variable domain of an antibody, methods to identify antigens which bind to antibodies comprising such improbable mutations, and methods of using such antigens to induce immune responses.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/