INDIA GLYCOLS LTD ENNATURE BIOPHARMA DIVISION;BHARTIA UMA SHANKAR
发明人:
BHARTIA UMA SHANKAR,BHARTIA UMA SHANKAR,KANDPAL JAI BALLABH,KANDPAL JAI BALLABH
申请号：
IN751/DEL/2012
公开号：
IN2012DE00751A
申请日:
2012.03.15
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
The present invention provides a simple single pot conversion method of Gingerol to high purity green Shogaol (6-Shogaol )from the ginger rhizome SCF- C02 extract, containing 40-45% Gingerol employing Multiple Separators of Very High Pressure Liquid Carbon dioxide by conducting basic or acidic dehydration, more preferably the conversion by 5-20% acid concentration at 80-90°C and separation of water from the crude shogaol conversion mixture by layer separation and further low pressure SCF- C02 extraction to get crude shogaol from 20-25% & Fractionating the crude Shogaol loaded in extraction vessel into the three separators namely high pressure (H.P). medium pressure (M.P) and low pressure (L.P) separators in series by variable simulation of the pressure and temperature individually between 1 10 bar and 50°C 50 bar and 40°C 40 bar and 20°C respectively and finally High purity green Shogaol is collected from H.P Separator having purity content of 29.3-40%. lower content green Shogaol fraction is collected from M.P Separator and water and some oil are collected from L.P Separator. The green Shogaol and formulation are suitable for its application in pharmaceutical, cosmetic and food industry.
