An oral care composition includes an effective amount of a basic amino acid in free or salt form;and an effective amount of calcium silicate particles. The calcium silicate particles have an average diameter of less than about 5 microns, such that they can occlude dentinal tubules of the teeth. An oral care method includes applying the composition to an oral cavity of a subject to reduce or inhibit hypersensitivity of the teeth and to achieve other benefits.一種口腔保健組成物,係包括一有效量之游離或鹽形式的鹼性胺基酸;一有效量之矽酸鈣粒子。該矽酸鈣粒子具有低於約5微米之平均粒徑,使其可封閉牙齒的牙本質小管。一種口腔保健方法,係包括將此組成物施予一對象之口腔,用以降低或抑制牙齒過敏及得到其他利益。