THE REGENTS OF THE UNIVERSITY OF MICHIGAN;KURA ONCOLOGY, INC.
发明人:
Jolanta GREMBECKA,Tomasz CIERPICKI,Dmitry BORKIN,Jonathan POLLOCK,Liansheng LI,Tao WU,Jun FENG,Pingda REN,Yi LIU
申请号：
US15578837
公开号：
US20180243303A1
申请日:
2016.06.03
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure provides compositions and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The compositions and methods of use are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin.
