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PROCÉDÉ DE PRODUCTION D'UN COMPOSITE MÉDICAMENT-COPOLYMÈRE SÉQUENCÉ ET PRODUIT PHARMACEUTIQUE CONTENANT LEDIT COMPOSITE
专利权人:
NIPPON KAYAKU KABUSHIKI KAISHA
发明人:
MOTOYAMA JUN
申请号:
EP11821842
公开号:
EP2612656A4
申请日:
2011.08.31
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
[Problem] There has been a requirement for a process for producing a pharmaceutical preparation that is obtained by encapsulating a uniform poorly water-soluble drug in a block copolymer, and dissolves immediately with an addition of water, and does not contain residues of organic solvents. [Solution] Provided is a method for producing a drug-block copolymer composite, the method comprising: mixing a poorly water-soluble drug and a block copolymer including a hydrophilic segment and a hydrophobic segment bonded together, in one or more non-aqueous solvents; optionally heating the mixture as necessary; and spray-drying the resulting mixture liquid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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