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Drug-block copolymer complex and method for producing medicament containing the same
专利权人:
日本化薬株式会社
发明人:
本山 順
申请号:
JP2012531907
公开号:
JP5886749B2
申请日:
2011.08.31
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
[Problem] There has been a requirement for a process for producing a pharmaceutical preparation that is obtained by encapsulating a uniform poorly water-soluble drug in a block copolymer, and dissolves immediately with an addition of water, and does not contain residues of organic solvents. [Solution] Provided is a method for producing a drug-block copolymer composite, the method comprising: mixing a poorly water-soluble drug and a block copolymer including a hydrophilic segment and a hydrophobic segment bonded together, in one or more non-aqueous solvents; optionally heating the mixture as necessary; and spray-drying the resulting mixture liquid.
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中国工程科技知识中心
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