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Process For Producing Drug-Block Copolymer Composite And Pharmaceutical Preparation Containing Same
专利权人:
Jun Motoyama
发明人:
Jun Motoyama
申请号:
US13818997
公开号:
US20130209390A1
申请日:
2011.08.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
[Problem] There has been a requirement for a process for producing a pharmaceutical preparation that is obtained by encapsulating a uniform poorly water-soluble drug in a block copolymer, and dissolves immediately with an addition of water, and does not contain residues of organic solvents.[Solution] Provided is a method for producing a drug-block copolymer composite, the method comprising: mixing a poorly water-soluble drug and a block copolymer including a hydrophilic segment and a hydrophobic segment bonded together, in one or more non-aqueous solvents; optionally heating the mixture as necessary; and spray-drying the resulting mixture liquid.
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