Growth differentiation factor-8 nucleic acid and polypeptide from aquatic species, and transgenic aquatic species

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专利权人:

THE JOHNS HOPKINS UNIVERSITY

发明人:

LEE SE-JIN,MCPHERRON ALEXANDRA C.

申请号：

US20040991343

公开号：

US2005216962(A1)

申请日:

2004.11.15

申请国别(地区):

美国

年份:

2005

代理人:

摘要：

A transgenic non-human aquatic organisms, such as piscine, crustacean, mollusks, and the like, having a transgene which results in disrupting the production of and/or activity of growth differentiation factor-8 (GDF-8) chromosomally integrated into the germ cells of the aquatic organism is disclosed. Also disclosed are methods for making such organisms and nucleic acid sequences encoding GDF-8 polypeptides from such aquatic organisms.

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