Cyril Y. Bowers,David H. Coy,Simon J. Hocart,Gloria S. Tannenbaum
申请号：
US13704052
公开号：
US09315546B2
申请日:
2011.06.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides novel peptides that can modulate the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and sub-types, isoforms and variants thereof). These peptides are useful as antagonists of the ghrelin receptor as well as inverse agonist, partial agonist or a combination of these activities as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, diabetes, central nervous system disorders, genetic disorders, and hyperpro-liferative disorders.
