BOWERS, CYRIL Y.,COY, DAVID H.,HOCART, SIMON J.,TANNENBAUM, GLORIA S.
申请号:
EP11796447
公开号:
EP2582715A4
申请日:
2011.06.16
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention provides novel peptides that can modulate the ghrelin receptor (growth hormone secretagogue receptor, GHS-R1a and sub-types, isoforms and variants thereof). These peptides are useful as antagonists of the ghrelin receptor as well as inverse agonist, partial agonist or a combination of these activities as medicaments for treatment and prevention of a range of medical conditions including, but not limited to, metabolic and/or endocrine disorders, gastrointestinal disorders, cardiovascular disorders, obesity and obesity-associated disorders, diabetes, central nervous system disorders, genetic disorders, and hyperpro-liferative disorders.