Constructions d'antigène utiles dans la détection et la différentiation d'anticorps du VIH

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专利权人:

ABBOTT LABORATORIES

发明人:

申请号：

EP08172729.9

公开号：

EP2055780B1

申请日:

1998.08.17

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

Isolated IIIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM 112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.

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