ПОЛІПЕПТИД, ЗДАТНИЙ ЗВЯЗУВАТИ С5-КОМПОНЕНТ КОМПЛЕМЕНТУ ЛЮДИНИ

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专利权人:

SWEDISH ORPHAN BIOVITRUM AB (PUBL)

发明人:

Nilsson, Joakim,Нільссон Йоаким,Nordling, Erik,Нордлінг Ерік,Stromberg, Patrik,Стрьомберг Патрік

申请号：

UA201603124

公开号：

UA117933C2

申请日:

2014.08.28

申请国别(地区):

UA

年份:

2018

代理人:

摘要：

The invention relates to a polypeptide capable of binding human complement component 5 (C5), said polypeptide comprising the amino acid sequence [BM]-[L2]-QSX42X43LLX46EAKKLX52X53X54Q wherein [BM] is a C5 bindingmotif [L2] is an interconnecting loop X42 is selected from A and S X43 is selected from N and E X46 is selected from A, S and C X52 is selected from E, N and S X53 is selected from D, E and S, provided that X53 is not D when X52 is N and X54 is selected from A and S.

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