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ORAL FORMULATIONS OF CHEMOTHERAPEUTIC AGENTS
专利权人:
Pankaj Modi
发明人:
Pankaj Modi
申请号:
US14184840
公开号:
US20150231069A1
申请日:
2014.02.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A composition and method of using the composition for treating a patient in need thereof, the composition comprising an oral formulation for enhanced bioavailability of therapeutic agents such as the taxane chemotherapeutic agents. The composition comprises the therapeutic agent and an absorption enhancing agent either co-administered with the agent or administered separately, the therapeutic agent in a polymer matrix resulting in a microbead and including an edible oil resulting in an emulsion. The absorption enhancing agent is a cyclosporin in one embodiment. The absorption enhancing agent is a P glycoprotein inhibitor in another embodiment.
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