NEW AMYANITINE CONJUGATES

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专利权人:

ХАЙДЕЛЬБЕРГ ФАРМА РИСЕЧ ГМБХ (DE)

发明人:

ЛУТЦ Кристиан (DE),АНДЕРЛЬ Ян (DE),МЮЛЛЕР Кристоф (DE),ЗИМОН Вернер (DE),ВЕРНЕР-ЗИМОН Сюзанне (DE),ХЕХЛЕР Торстен (DE),КУЛЬКЕ Михаэль (DE)

申请号：

RU2018131636

公开号：

RU2018131636A

申请日:

2017.03.02

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

The invention relates to a conjugate comprising (a) an amatoxin comprising (i) an amino acid 4 with a 6'-deoxy position； and (ii) an amino acid 8 with an S-deoxy position； (b) a target-binding moiety； and (c) optionally a linker linking said amatoxin and said target-binding moiety. The invention furthermore relates to a pharmaceutical composition comprising such conjugate.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/