AMANITIN CONJUGATES

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专利权人:

하이델베르크 파마 리서치 게엠베하

发明人:

루츠 크리스티안,안데를 얀,뮐러 크리스토퍼,지몬 베르너,베르너-지몬 수잔,헤흘레어 토어스텐,쿨케 미카엘

申请号：

KR1020187027424

公开号：

KR1020180114191A

申请日:

2017.03.02

申请国别(地区):

KR

年份:

2018

代理人:

摘要：

The invention relates to a conjugate comprising (a) an amatoxin comprising (i) an amino acid 4 with a 6-deoxy position and (ii) an amino acid 8 with an S-deoxy position (b) a target-binding moiety and (c) optionally a linker linking said amatoxin and said target-binding moiety. The invention furthermore relates to a pharmaceutical composition comprising such conjugate.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/