Pharmaceutical composition comprising a 15-PGDH inhibitor for use in the enhancement of cell transplantation, organ transplantation, tissue graft grafting, organ regeneration, tissue regeneration, tissue repair, wound healing, growth and / or cell proliferation and / or palliation of cell and / or tissue graft rejection, in which the 15-PGDH inhibitor has the following formula (III): ** Formula ** in which: n is 0-2； R1 is a C1-8 alkyl, which is linear, branched or cyclic and which is unsubstituted or substituted； R2 and R3 are the same or different and each is selected from the group consisting of H, a lower alkyl group, (CH2) n1OR '(in which n1>； = 1, 2 or 3), CF3, CH2-CH2X, O -CH2-CH2X, CH2-CH2-CH2X, O-CH2-CH2X (where X>； = F, Cl, Br or I), CN, (C>； = O) -R ', (C>； = O) N (R ') 2, O (CO) R' and COOR '(where R' is H or a lower alkyl group)； Z1 is NR ', O or S (where R' is H or a lower alkyl group)； X is N or CH； R6 and R7 are optional and, if present, are the same or different and each is selected from the group consisting of an H, F, Cl, Br, I, a lower alkyl group, (CH2) n1OR '(in which n1>； = 1, 2 or 3), CF3, CH2-CH2X, O-CH2- CH2X, CH2-CH2-CH2X, O-CH2-CH2X (where X>； = F, Cl, Br or I), CN , (C>； = O) -R ', N (R') 2, NO2, (C>； = O) N (R ') 2, O (CO) R', OR ', SR', COOR '(in which R 'is H or a lower alkyl group)； substituted or unsubstituted aryl, heteroaryl, cycloalkyl or heterocyclyl, and pharmaceutically acceptable salts thereof.Composición farmacéutica que comprende un inhibidor de 15-PGDH para su uso en la potenciación del trasplante de células, trasplante de órganos, injerto de injertos de tejidos, regeneración de órganos, regeneración de tejidos, reparación de tejidos, cicatrización de heridas, crecimiento y/o proliferación celular y/o paliación del rechazo de injertos de células y/o tejidos, en la que el inhibidor de 15-PGDH tiene la siguiente fórmula (III):**Fórmula** en la que: n es 0-2； R1 es un alquilo C1-8, que es lineal, ramificado o
