THE UAB RESEARCH FOUNDATION;LEADIANT BIOSCIENCES S.P.A.
发明人:
RALPH D. SANDERSON,VISHNU PRAKASH C. RAMANI,ALESSANDRO NOSEDA,PAOLA BARBIERI
申请号:
PT16709148
公开号:
PT3265075T
申请日:
2016.03.03
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The present invention relates to roneparstat for use in a combined therapy for the treatment of multiple myeloma. In particular it has unexpectedly been found that the combined use of roneparstat with a proteasome inhibitor, in particular selected between bortezomib and carfilzomib improve efficacy in decreasing the overall tumor burden, especially showing synergism, with respect to the administration of each active ingredient alone.