Leadiant Biosciences S.p.A.;The UAB Research Foundation
发明人:
SANDERSON, RALPH D.,PRAKASH C. RAMANI, VISHNU,NOSEDA, ALESSANDRO,BARBIERI, PAOLA
申请号:
PL16709148
公开号:
PL3265075T3
申请日:
2016.03.03
申请国别(地区):
PL
年份:
2020
代理人:
摘要:
The present invention relates to roneparstat for use in a combined therapy for the treatment of multiple myeloma. In particular it has unexpectedly been found that the combined use of roneparstat with a proteasome inhibitor, in particular selected between bortezomib and carfilzomib improve efficacy in decreasing the overall tumor burden, especially showing synergism, with respect to the administration of each active ingredient alone.