SIGMA-TAU RESEARCH SWITZERLAND S.A.;THE UAB RESEARCH FOUNDATION
发明人:
Ralph D. Sanderson,Vishnu Prakash C. Ramani,Alessandro Noseda,Paola Barbieri
申请号：
US15556183
公开号：
US20180050061A1
申请日:
2016.03.03
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to roneparstat for use in a combined therapy for the treatment of multiple myeloma. In particular it has unexpectedly been found that the combined use of roneparstat with a proteasome inhibitor, in particular selected between bortezomib and carfilzomib or with melphalan improve efficacy in decreasing the overall tumor burden, especially showing synergism, with respect to the administration of each active ingredient alone.
