LEADIANT BIOSCIENCES S.A.;THE UAB RESEARCH FOUNDATION
发明人:
SANDERSON, RALPH D.,PRAKASH C. RAMANI, VISHNU,NOSEDA, ALESSANDRO,BARBIERI, PAOLA
申请号:
CA2978040
公开号:
CA2978040A1
申请日:
2016.03.03
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to roneparstat for use in a combined therapy for the treatment of multiple myeloma. In particular it has unexpectedly been found that the combined use of roneparstat with a proteasome inhibitor, in particular selected between bortezomib and carfilzomib or with melphalan improve efficacy in decreasing the overall tumor burden, especially showing synergism, with respect to the administration of each active ingredient alone.