Allan C. Shaw,Charlotte Helgstrand,Michael P. Bastner Sandrini,Sebastian B. Joergensen,Henning Thoegersen,Kristian Sass-Oerum,Sven Hastrup,Kim V. Andersen
申请号:
US15000637
公开号:
US20160129083A1
申请日:
2016.01.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to MIC-1 fusion proteins. More specifically it relates to compounds comprising fusion proteins comprising a MIC-1 protein or an analogue thereof at the C-terminus of the fusion protein and a functional variant of human serum albumin at the N-terminus of the fusion protein connected via a peptide linker. The compounds of the invention have MIC-1 activity. The invention also relates to pharmaceutical compositions comprising such compounds and pharmaceutically acceptable excipients, as well as the medical use of the compounds.