Allan Christian Shaw,Charlotte Helgstrand,Michael Paolo Bastner Sandrini,Sebastian Beck Joergensen,Henning Thoegersen,Kristian Saas-Oerum,Sven Hastrup,Kim Vilbour Andersen
申请号:
US14742159
公开号:
US20160015784A1
申请日:
2015.06.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to MIC-1 fusion proteins. More specifically it relates to compounds comprising fusion proteins comprising a MIC-1 protein or an analogue thereof at the C-terminus of the fusion protein and a functional variant of human serum albumin at the N-terminus of the fusion protein connected via a peptide linker. The compounds of the invention have MIC-1 activity. The invention also relates to pharmaceutical compositions comprising such compounds and pharmaceutically acceptable excipients, as well as the medical use of the compounds.