REVETS HILDE ADI PIERRETTE,HOFMEISTER ROBERT,KNUEHL CHRISTINE,HOCK BJOERN,BESTE GERALD,VERDONCK FRANK KAMIEL DELPHINA,CORNELIS SIGRID GODELIEVE VICTOR
申请号：
NZ60357011
公开号：
NZ603570A
申请日:
2011.05.20
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
The present disclosure relates to amino acid sequences that are directed against human HER3 comprising at least two immunoglobulin single variable domains (ISVs), wherein the first ISV is a 17B05-like sequence and the second ISV is a 21F06-like sequence. The disclosure also relates to nucleic acids encoding such amino acid sequences and polypeptides and to use of the protein in the manufacture of a medicament to treat cancers or disorders related to nerve regeneration.
