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her3-related biological materials.
专利权人:
Ablynx N.V.;MERCK PATENT GMBH
发明人:
Bjoern Hock,Christine Knuehl,Frank Kamiel Delphina Verdonck,Gerald Beste,Hilde Adi Pierrette Revets,Robert Hofmeister,Sigrid Godelie Victor Cornelis
申请号:
BR112012029588
公开号:
BR112012029588A2
申请日:
2011.05.20
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
her3-related biological materials - the present invention relates to amino acid sequences that are directed (as defined in this application) against her3, as well as to compounds or constructs, and in particular proteins and polypeptides, which comprise or essentially consist of one or more further such amino acid sequences (also referred to herein as "amino acid sequences of the invention", compounds of the invention, and "polypeptides of the invention, respectively). the invention also relates to nucleic acids encoding such amino acid sequences and polypeptides (also referred to herein as "nucleic acids of the invention" or "nucleotide sequences of the invention"); methods for preparing such amino acid and polypeptide sequences; host cells expressing or capable of expressing such amino acid or polypeptide sequences; to compositions, and in particular pharmaceutical compositions comprising such amino acid sequences, polypeptides, nucleic acids and / or host cells; and the uses of such amino acid or polypeptide sequences, nucleic acids, host cells and / or compositions, in particular for prophylactic, therapeutic or diagnostic purposes, such as the prophylactic, therapeutic or diagnostic purposes mentioned in this application.materiais biológicos relacionados a her3 - a presente invenção refere-se a sequências de aminoácidos que são direcionadas (como definidas neste pedido) contra her3, bem como a compostos ou construtos, e em particular proteínas e polipeptídeos, que compreendem ou essencilamente consistem em uma ou mais tais sequências de aminoácidos (também referidas neste pedido como "sequências de aminoácidos da invenção", compostos da invenção, e "polipeptídeos da invenção, respectivamente). a invenção também se refere a ácidos nucleicos que codificam tais sequências de aminoácidos e poliptídeos (também referidos neste pedido como "ácidos nucleicos da invenção" ou "sequências nucleotídicas da invenção") ; a métodos para preparação de tais sequências de aminoá
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