PNEUMOLYSIN MUTANTS AND METHODS OF USE THEREOF

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专利权人:

发明人:

TWETEN RODNEY K

申请号：

IN201717021601

公开号：

IN201717021601A

申请日:

2017.06.20

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The present disclosure provides in various embodiments immunogenic mutants of cholesterol dependent cytolysins such as pneumolysin which have reduced hemolytic activity and reduced pore forming activity in comparison to their wild type protein. The present disclosure also provides in various embodiments nucleic acids which encode such mutants and methods of the use of such mutants.

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中国工程科技知识中心

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http://www.ckcest.cn/home/