Paul D. Lyne;Jose William Saldanha;Michael Karpusas;Ellen A. Garber
发明人:
Michael Karpusas,Paul D. Lyne,Jose William Saldanha,Ellen A. Garber
申请号：
US13297124
公开号：
US20120177638A1
申请日:
2011.11.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.
