Michael Karpusas,Paul D. Lyne,Ellen A. Garber Stark,Jose William Saldanha
申请号：
US14597262
公开号：
US09644030B2
申请日:
2015.01.15
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.
