Procédé de préparation d'une formulation liquide à concentration élevée d'un anticorps

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专利权人:

Takeda GmbH

发明人:

申请号：

EP12190855.2

公开号：

EP2727602A1

申请日:

2012.10.31

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides a method for preparation of a high concentration liquid formulation (HCLF) of an antibody or a fragment thereof. The present invention also relates to a method for stabilizing an anti-CD20 antibody or a fragment thereof in a liquid pharmaceutical formulation. Furthermore, the present invention relates to a liquid pharmaceutical formulation of a veltuzumab antibody or a fragment thereof comprising at least 155 mg/mL of a veltuzumab antibody or a fragment thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/