PROBLEM TO BE SOLVED: To provide a new therapeutic agent for ovarian clear cell adenocarcinoma targeted for a protein specifically developed in this disease.SOLUTION: A therapeutic agent and/or a preventive agent of clear cell adenocarcinoma includes a substance which can inhibit the function of or suppress the development of, the N-myc downstream regulated gene 1 protein in a clear cell adenocarcinoma cell. A drug that reduces the anticancer drug resistance of clear cell adenocarcinoma contains a substance which can inhibit the function of or suppress the development of, the N-myc downstream regulated gene 1 protein in a clear cell adenocarcinoma cell.COPYRIGHT: (C)2013,JPO&INPIT【課題】 卵巣明細胞腺癌に特異的に発現しているタンパク質を標的とした本疾患の新しい治療薬を提供すること。【解決手段】 明細胞腺癌細胞におけるN-myc下流制御遺伝子1タンパク質の機能を阻害若しくは発現を抑制することができる物質を含む、明細胞腺癌の治療及び/又は予防剤。明細胞腺癌細胞におけるN-myc下流制御遺伝子1タンパク質の機能を阻害若しくは発現を抑制することができる物質を含む、明細胞腺癌の抗癌剤耐性を低下させる薬剤。【選択図】図4
