LTD.;THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV
发明人:
ZARETZKY, MARIANNA,AHARONI, AMIR
申请号：
CA2842067
公开号：
CA2842067A1
申请日:
2012.07.18
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Provided are engineered soluble hIL-17RA receptors with high affinity to hIL-17 that inhibit downstream IL17A induced signaling events in cells. Also provided are methods of inhibiting hIL-17A induced secretion of CXCL1 and/or IL-6 in cells, as well as methods of treating inflammation and/or inflammatory disorders in a subject.
