University of Florida Research Foundation; Incorporated
发明人:
Gregory Allan Hudalla II,Margaret Mary Fettis
申请号:
US16755553
公开号:
US20200262882A1
申请日:
2018.10.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Described herein are modified gall monomers that can contain one or more mutated cysteines and/or can be pegylated. Also described herein are modified gall dimers, trimers, and tetramers that can contain one or more modified gall monomers as described herein. Also described herein are pharmaceutical formulations containing a modified gall monomer, dimer, trimer, and/or tetramer. Also described herein are methods of making the modified gall polypeptides and complexes thereof. Also described herein are methods of using the modified gall polypeptides and complexes thereof.