Anikó GÖBLYÖS;Johannes BRUSSEE;Adriaan P. IJZERMAN;Zhan-Guo GAO;Kenneth JACOBSON
发明人:
Anikó GÖBLYÖS,Johannes BRUSSEE,Adriaan P. IJZERMAN,Zhan-Guo GAO,Kenneth JACOBSON
申请号：
US13800560
公开号：
US20130197025A1
申请日:
2013.03.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The claimed subject matter relates to allosteric modulation of A3 adenosine receptor (A3AR) and provides for the use of an A3 adenosine receptor modulator (A3RM), for the preparation of pharmaceutical compositions for modulating the A3AR in a subject, as well as pharmaceutical compositions including the same and therapeutic methods including administering to a subject an amount of an A3RM, the amount being effective to modulate A3AR activity. The A3RM according to claimed subject matter are 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives. Also provided are 1H-Imidazo-[4,5-c]quinolin-4-amine derivatives.
