PROBLEM TO BE SOLVED: To provide an inhibitor of blood GIP concentration rise in which the blood GIP (Gastric Inhibitory Polypeptide) concentration rise is effectively controlled, and thereby which is useful for the decrease, prevention, improvement, moderation or treatment of crisis risk of slow digestion； digestion promotion； and the decrease, prevention, improvement, moderation or treatment of crisis risk of obesity or insulin resistance.SOLUTION: The inhibitor of blood GIP concentration rise includes a polyglutamic acid in which a carboxyl group of a &gamma； position and an amino group of an &alpha； position of glutamic acid are peptide-bonded and at least 50% of a hydrogen atom of the carboxyl group is substituted with potassium, as an active constituent.【課題】血中のＧＩＰ（消化管ホルモン）濃度上昇を効果的に抑制することで、胃もたれの発症リスクの低下・予防・改善・緩和・処置、消化の促進、および肥満やインスリン抵抗性の発症リスクの低下・予防・改善・緩和・処置に有用な血中ＧＩＰ濃度上昇抑制剤を提供する。【解決手段】グルタミン酸のγ位のカルボキシル基とα位のアミノ基がペプチド結合したポリグルタミン酸でそのカルボキシル基の水素原子の５０％以上がカリウムに置換されたものを有効成分として含有する血中ＧＩＰ濃度上昇抑制剤。【選択図】なし
