MONAHAN, JOHN E.,孟娜汉 约翰E,孟娜漢 約翰E,LI, FANG,李昉,孟娜汉 约翰E,孟娜漢 約翰E
申请号:
TW101139801
公开号:
TW201332550A
申请日:
2012.10.26
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
The present invention relates to a method of treating gastrointestinal stromal tumors (GIST), especially GIST, which is progressing after imatinib therapy or after imatinib and sunitinib therapy, using a combination comprising (a) a c-kit inhibitor and (b) a PI3K inhibitor or FGFR inhibitor.本發明係關於使用包含(a)c-kit抑制劑及(b)PI3K抑制劑或FGFR抑制劑之組合治療胃腸道基質瘤(GIST),尤指在伊馬替尼(imatinib)療法或伊馬替尼及舒尼替尼(sunitinib)療法之後惡化之GIST之方法。