Edward James OLHAVA,Angelos DOVLETOGLOU,Steve WALD,Bruce REHLAENDER
申请号：
US16433259
公开号：
US20190388335A1
申请日:
2019.06.06
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides injectable formulations of (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol and hydrates thereof and methods for treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders.
