Olhava, Edward James,Dovletoglou, Angelos,Wald, Steve,Rehlaender, Bruce
申请号:
AU2015317509
公开号:
AU2015317509A1
申请日:
2015.09.17
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention provides injectable formulations of (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol and hydrates thereof and methods for treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders.