OLHAVA, EDWARD JAMES,DOVLETOGLOU, ANGELOS,REHLANENDER, BRUCE
申请号：
EP14770498
公开号：
EP2968390A4
申请日:
2014.03.14
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
The present invention provides injectable formulations of (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol and hydrates thereof and methods for treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders.
