COMPOSES CYCLIQUES UTILES EN TANT QUE MODULATEURS DU TNF ALPHA

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

XIAO, HAI-YUN,DHAR, MURALI T.G.,JIANG, BIN,DUAN, JINGWU

申请号：

CA2994703

公开号：

CA2994703A1

申请日:

2016.08.02

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Disclosed are compounds of Formula (I) or a salt thereof, wherein: Ring A is 3- to 6-membered carbocyclic or heterocyclic ring； X is CR1 or N； Y is -(CR5R5)m-； Z is -(CR5R5)n-； and q, R1, R2, R3, R4, R6, R7, R8, R9, and R10 are defined herein. Also disclosed are methods of using such compounds as modulators of TNFa, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

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