ANANDA M. CHAKRABARTY,TAPAS K. DAS GUPTA,VASU PUNJ,OLGA ZABORINA,YOSHINORI HIRAOKA,TOHRU YAMADA
申请号:
US14075994
公开号:
US20140179617A1
申请日:
2013.11.08
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death or uncontrolled growth. The present inventors have found that different microorganisms produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer.