The present disclosure relates to a homeopathy based formulation. The homeopathy based formulation comprises at least one potentized mixture of malaria nosode, and a vehicle. The malaria nosode can be obtained from at least one malaria parasite selected from the group consisting of Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, Plasmodium vivax, and combinations thereof. The ratio of the potentized mixture of malaria nosode to the vehicle is in the range of 1:9 for 1X potency and 1:99 for 1C potency. The present disclosure also provides a process for preparing a homeopathy based formulation. The homeopathy based formulation of the present disclosure can be used in the treatment of malaria.
